Goal
It’s unsure whether or not percutaneous coronary intervention (PCI) along with optimum medical remedy (OMT) can cut back opposed medical occasions in the long run as in contrast with OMT alone in sufferers with pure secure angina.
Strategies
We enrolled sufferers from 2006 to 2010 utilizing the Korean nationwide insurance coverage knowledge. 58 742 sufferers with pure secure angina with no historical past of myocardial infarction (MI) nor PCI had been candidate, and at last, 5673 sufferers within the PCI plus OMT group and 5673 within the OMT alone group had been chosen with 1:1 propensity matching. They had been adopted up for 9.3 years.
Outcomes
Major endpoint, a composite of MI, stroke and cardiac dying charge was considerably increased within the PCI group than within the OMT group, 13.5/1000 vs 11.5/1000 person-year with HR of 1.18 (95% CI 1.06 to 1.32, p=0.003). Particular person occasion charge of MI and cardiac dying charge was increased within the PCI group than within the OMT group at 9.3 years, 2.9 vs 2.1 (HR 1.38, 95% CI 1.09 to 1.7, p=0.009) and 4.8 vs 3.4/1000 person-year (HR 1.40, 95% CI 1.16 to 1.69, p=0.001), respectively. Revascularisation and complete dying occurred extra within the PCI group as in contrast with the OMT group, 30.3 vs 8.2 (HR 3.64, 95% CI 3.27 to 4.05, p<0.001) and 13.5 vs 10.6/1000 person-year (HR 1.23, 95% CI 1.12 to 1.40, p<0.001), respectively. In subgroup evaluation, the identical pattern of extra occasion within the PCI group was detected.
Conclusions
PCI plus OMT was related to increased charge of main endpoint of MI, stroke, cardiac dying as in contrast with OMT alone in sufferers with pure secure angina at 9.3-year follow-up in massive inhabitants.